Robert G. Siman: search on Z-Library

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1

Evidence That the Blood Biomarker SNTF Predicts Brain Imaging Changes and Persistent Cognitive Dysfunction in Mild TBI Patients

Siman, Robert, Giovannone, Nicholas, Hanten, Gerri, Wilde, Elisabeth A., McCauley, Stephen R., Hunter, Jill V., Li, Xiaoqi, Levin, Harvey S., Smith, Douglas H.

Journal:

Frontiers in Neurology

Year:

2013

Language:

english

File:

PDF, 574 KB

english, 2013

2

E2F1 induces cell death, calpain activation, and MDMX degradation in a transcription independent manner implicating a novel role for E2F1 in neuronal loss in SIV encephalitis

Gordon D. Strachan, Maya A. Koike, Robert Siman, David J. Hall, Kelly L. Jordan-Sciutto

Journal:

Journal of Cellular Biochemistry

Year:

2005

Language:

english

File:

PDF, 264 KB

english, 2005

3

Caspase-3 activation in oligodendrocytes from the myelin-deficient rat

Jacqueline S. Beesley, LeaAnn Lavy, Nuri B. Eraydin, Robert Siman, Judith B. Grinspan

Journal:

Journal of Neuroscience Research

Year:

2001

Language:

english

File:

PDF, 180 KB

english, 2001

4

Potent α-ketocarbonyl and boronic ester derived inhibitors of proteasome

Mohamed Iqbal, Sankar Chatterjee, James C. Kauer, John P. Mallamo, Patricia A. Messina, Alyssa Reiboldt, Robert Siman

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 160 KB

english, 1996

5

Potent fluoromethyl ketone inhibitors of recombinant human calpain I

Sankar Chatterjee, Kurt Josef, Gregory Wells, Mohamed Iqbal, Ron Bihovsky, John P. Mallamo, Mark A. Ator, Donna Bozyczko-Coyne, Satish Mallya, Shobha Senadhi, Robert Siman

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 230 KB

english, 1996

6

Neuroprotection with delayed initiation of prolonged hypothermia after in vitro transient global brain ischemia

Eric J. Lawrence, Eva Dentcheva, Kevin M. Curtis, Victoria L. Roberts, Robert Siman, Robert W. Neumar

Journal:

Year:

2005

Language:

english

File:

PDF, 154 KB

english, 2005

7

Strategies to alter the progression of Alzheimer's disease

Robert Siman, Richard W. Scott

Journal:

Current Opinion in Biotechnology

Year:

1996

Language:

english

File:

PDF, 670 KB

english, 1996

8

Xanthene derived potent nonpeptidic inhibitors of recombinant human calpain I

Sankar Chatterjee, Mohamed Iqbal, James C. Kauer, John P. Mallamo, Shobha Senadhi, Satish Mallya, Donna Bozyczko-Coyne, Robert Siman

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1996

Language:

english

File:

PDF, 230 KB

english, 1996

9

Nonpeptidic inhibitors of recombinant human calpain I

Sankar Chatterjee, Shobha Senadhi, Donna Bozyczko-Coyne, Robert Siman, John P. Mallamo

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 182 KB

english, 1997

10

Subsite requirements for peptide aldehyde inhibitors of human calpain I

Mohamed Iqbal, Patricia A. Messina, Bethany Freed, Manoj Das, Sankar Chatterjee, Rabindranath Tripathy, Ming Tao, Kurt A. Josef, Bruce Dembofsky, Derek Dunn, Eric Griffith, Robert Siman, Shobha E. Sen

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1997

Language:

english

File:

PDF, 329 KB

english, 1997

11

P2-achiral, P'-extended α-ketoamide inhibitors of calpain I

Sankar Chatterjee, Derek Dunn, Ming Tao, Gregory Wells, Zi-Qiang Gu, Ron Bihovsky, Mark A. Ator, Robert Siman, John P. Mallamo

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 209 KB

english, 1999

12

Exploration of the importance of the P2-P3 -NHCO-Moiety in a potent di- or tripeptide inhibitor of calpain i: insights into the development of nonpeptidic inhibitors of calpain I

Sankar Chatterjee, Mohamed Iqbal, Satish Mallya, Shobha E. Senadhi, Teresa M. O’Kane, Beth Ann McKenna, Donna Bozyczko-Coyne, James C. Kauer, Robert Siman, John P. Mallamo

Journal:

Bioorganic & Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 257 KB

english, 1998

13

K-252a Induces Tyrosine Phosphorylation of the Focal Adhesion Kinase and Neurite Outgrowth in Human Neuroblastoma SH-SY5Y Cells

Anna Coco Maroney, Lorraine Lipfert, M. Elizabeth Forbes, Marcie A. Glicksman, Nicola T. Neff, Robert Siman, Craig A. Dionne

Journal:

Journal of Neurochemistry

Year:

1995

Language:

english

File:

PDF, 1.56 MB

english, 1995

14

Localization of presenilin–nicastrin complexes and γ-secretase activity to the trans-Golgi network

Robert Siman, Jamel Velji

Journal:

Journal of Neurochemistry

Year:

2003

Language:

english

File:

PDF, 179 KB

english, 2003

15

Activation of calpain-1 in myelin and microglia in the white matter of the aged rhesus monkey

Jason D. Hinman, James A. Duce, Robert A. Siman, William Hollander, Carmela R. Abraham

Journal:

Journal of Neurochemistry

Year:

2004

Language:

english

File:

PDF, 444 KB

english, 2004

16

The ultrastructural localization of calcium-activated protease “calpain” in rat brain

Lynn S. Perlmutter, Robert Siman, Christine Gall, Peter Seubert, Michel Baudry, Gary Lynch

Journal:

Year:

1988

Language:

english

File:

PDF, 5.24 MB

english, 1988

17

Rapid recovery of nicotinic receptor-mediated sodium-22 influx following withdrawal from acute or chronic cholinergic stimulation

Robert G. Siman, William L. Klein

Journal:

Cellular and Molecular Neurobiology

Year:

1982

Language:

english

File:

PDF, 415 KB

english, 1982

18

Temporal Profiles of Cytoskeletal Protein Loss following Traumatic Axonal Injury in Mice

Gulyeter Serbest, Matthew F. Burkhardt, Robert Siman, Ramesh Raghupathi, Kathryn E. Saatman

Journal:

Neurochemical Research

Year:

2007

Language:

english

File:

PDF, 383 KB

english, 2007

19

Specificity of Muscarinic Acetylcholine Receptor Regulation by Receptor Activity

Robert G. Siman, William L. Klein

Journal:

Journal of Neurochemistry

Year:

1981

Language:

english

File:

PDF, 985 KB

english, 1981

20

Purification from Synaptosomal Plasma Membranes of Calpain I, a Thiol Protease Activated by Micromolar Calcium Concentrations

Robert Siman, Michel Baudry, Gary Lynch

Journal:

Journal of Neurochemistry

Year:

1983

Language:

english

File:

PDF, 661 KB

english, 1983

21

Identification and Characterization of Calcium-Dependent Metalloproteases in Rat Brain

Robert B. Nelson, Robert Siman

Journal:

Journal of Neurochemistry

Year:

1989

Language:

english

File:

PDF, 1.09 MB

english, 1989

22

Glutamate Neurotoxicity Is Independent of Calpain I Inhibition in Primary Cultures of Cerebellar Granule Cells

Hari Manev, Marco Favaron, Robert Siman, Alessandro Guidotti, Erminio Costa

Journal:

Journal of Neurochemistry

Year:

1991

Language:

english

File:

PDF, 2.16 MB

english, 1991

23

Identification of a Chymotrypsin-Like Mast Cell Protease in Rat Brain Capable of Generating the N-Terminus of the Alzheimer Amyloid β-Protein

Robert B. Nelson, Robert Siman, Mohamed A. Iqbal, Huntington Potter

Journal:

Journal of Neurochemistry

Year:

1993

Language:

english

File:

PDF, 1.32 MB

english, 1993

24

Aurintricarboxylic Acid Protects Hippocampal Neurons from NMDA-and Ischemia-Induced Toxicity In Vivo

Jill M. Roberts-Lewis, Val R. Marcy, Yonghua Zhao, Jeffry L. Vaught, Robert Siman, Michael E. Lewis

Journal:

Journal of Neurochemistry

Year:

1993

Language:

english

File:

PDF, 559 KB

english, 1993

25

Regulation of glutamate receptor binding by the cytoskeletal protein fodrin

Siman, Robert, Baudry, Michel, Lynch, Gary

Journal:

Year:

1985

File:

PDF, 549 KB

1985

26

Novel dipeptidyl proteasome inhibitors overcome Bcl-2 protective function and selectively accumulate the cyclin-dependent kinase inhibitor p27 and induce apoptosis in transformed, but not normal, human fibroblasts

An, Bing, Goldfarb, Ronald H, Siman, Robert, Dou, Q Ping

Journal:

Cell Death & Differentiation

Year:

1998

Language:

english

File:

PDF, 1.17 MB

english, 1998

27

Novel surrogate markers for acute brain damage: cerebrospinal fluid levels corrrelate with severity of ischemic neurodegeneration in the rat

Siman, Robert, Zhang, Chen, Roberts, Victoria L, Pitts-Kiefer, Alex, Neumar, Robert W

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2005

Language:

english

File:

PDF, 349 KB

english, 2005

28

Regional distribution and time-course of calpain activation following kainate-induced seizure activity in adult rat brain

Xiaoning Bi, Vanessa Chang, Robert Siman, Georges Tocco, Michel Baudry

Journal:

Year:

1996

Language:

english

File:

PDF, 6.70 MB

english, 1996

29

Caspase-mediated cell death predominates following engraftment of neural progenitor cells into traumatically injured rat brain

Asha Bakshi, Carrie A. Keck, Vadim S. Koshkin, David G. LeBold, Robert Siman, Evan Y. Snyder, Tracy K. McIntosh

Journal:

Year:

2005

Language:

english

File:

PDF, 676 KB

english, 2005

30

Biomarker evidence for mild central nervous system injury after surgically-induced circulation arrest

Robert Siman, Victoria L. Roberts, Elizabeth McNeil, Antony Dang, Joseph E. Bavaria, Sindhu Ramchandren, Michael McGarvey

Journal:

Year:

2008

Language:

english

File:

PDF, 628 KB

english, 2008

31

Traumatic mechanical injury to the hippocampus in vitro causes regional caspase-3 and calpain activation that is influenced by NMDA receptor subunit composition

Michael N. DeRidder, Melissa J. Simon, Robert Siman, Yves P. Auberson, Ramesh Raghupathi, David F. Meaney

Journal:

Neurobiology of Disease

Year:

2006

Language:

english

File:

PDF, 890 KB

english, 2006

32

Glutamate receptor antagonists inhibit calpain-mediated cytoskeletal proteolysis in focal cerebral ischemia

Stephen L Minger, James W Geddes, Mary L Holtz, Susan D Craddock, Sidney W Whiteheart, Robert G Siman, L.Creed Pettigrew

Journal:

Year:

1998

Language:

english

File:

PDF, 10.86 MB

english, 1998

33

Mechanisms of calpain mediated proteolysis of voltage gated sodium channel α-subunits following in vitro dynamic stretch injury

Catherine R. von Reyn, Rosalind E. Mott, Robert Siman, Douglas H. Smith, David F. Meaney

Journal:

Journal of Neurochemistry

Year:

2012

Language:

english

File:

PDF, 790 KB

english, 2012

34

A Sensitive, Continuously Recording Fluorogenic Assay for Calpain

Satish K. Mallya, Sheryl Meyer, Donna Bozyczko–Coyne, Robert Siman, Mark A. Ator

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 76 KB

english, 1998

35

Calpain Activity in the Rat Brain after Transient Forebrain Ischemia

Robert W. Neumar, Frank H. Meng, Angela M. Mills, Y.Anne Xu, Chen Zhang, Frank A. Welsh, Robert Siman

Journal:

Experimental Neurology

Year:

2001

Language:

english

File:

PDF, 380 KB

english, 2001

36

Distinct Nuclear and Cytoplasmic Localization of Caspase Cleavage Products in Two Models of Induced Apoptotic Death in Dopamine Neurons of the Substantia Nigra

Tinmarla F. Oo, Robert Siman, Robert E. Burke

Journal:

Experimental Neurology

Year:

2002

Language:

english

File:

PDF, 240 KB

english, 2002

37

Comparison of Calpain and Caspase Activities in the Adult Rat Brain after Transient Forebrain Ischemia

Chen Zhang, Robert Siman, Y.Anne Xu, Angela M. Mills, James R. Frederick, Robert W. Neumar

Journal:

Neurobiology of Disease

Year:

2002

Language:

english

File:

PDF, 987 KB

english, 2002

38

β-Amyloid precursor is a PEST protein

Robert Siman, Greg Christoph

Journal:

Biochemical and Biophysical Research Communications

Year:

1989

Language:

english

File:

PDF, 550 KB

english, 1989

39

Regulation by calcium ions of glutamate receptor binding in hippocampal slices

Michel Baudry, Robert Siman, Elizabeth K. Smith, Gary Lynch

Journal:

European Journal of Pharmacology

Year:

1983

Language:

english

File:

PDF, 626 KB

english, 1983

40

A CBP Binding Transcriptional Repressor Produced by the PS1/ϵ-Cleavage of N-Cadherin Is Inhibited by PS1 FAD Mutations

Philippe Marambaud, Paul H Wen, Anindita Dutt, Junichi Shioi, Akihiko Takashima, Robert Siman, Nikolaos K Robakis

Journal:

Year:

2003

Language:

english

File:

PDF, 544 KB

english, 2003

41

Long-lasting impairment in hippocampal neurogenesis associated with amyloid deposition in a knock-in mouse model of familial Alzheimer's disease

Chen Zhang, Elizabeth McNeil, Lindsay Dressler, Robert Siman

Journal:

Experimental Neurology

Year:

2007

Language:

english

File:

PDF, 1.38 MB

english, 2007

42

Proteins released from degenerating neurons are surrogate markers for acute brain damage

Robert Siman, Tracy K McIntosh, Kristie M Soltesz, Zhaoming Chen, Robert W Neumar, Victoria L Roberts

Journal:

Neurobiology of Disease

Year:

2004

Language:

english

File:

PDF, 863 KB

english, 2004

43

Developmental status of neurons selectively vulnerable to rapidly triggered post-ischemic caspase activation

Zhaoming Chen, Diana Kontonotas, Daniel Friedmann, Alex Pitts-Kiefer, James R. Frederick, Robert Siman, Robert W. Neumar

Journal:

Neuroscience Letters

Year:

2005

Language:

english

File:

PDF, 367 KB

english, 2005

44

Combination therapy prevents amyloid-dependent and -independent structural changes

Gauri Malthankar-Phatak, Shane Poplawski, Nikhil Toraskar, Robert Siman

Journal:

Neurobiology of Aging

Year:

2012

Language:

english

File:

PDF, 4.17 MB

english, 2012

45

Long-Term Accumulation of Amyloid-β, β-Secretase, Presenilin-1, and Caspase-3 in Damaged Axons Following Brain Trauma

Xiao-Han Chen, Robert Siman, Akira Iwata, David F. Meaney, John Q. Trojanowski, Douglas H. Smith

Journal:

The American Journal of Pathology

Year:

2004

Language:

english

File:

PDF, 3.50 MB

english, 2004

46

Presenilin P264L knock-in mutation: Differential effects on abproduction, amyloid deposition, and neuronal vulnerability

Robert Siman, Andrew G. Reaume, Mary J. Savage, Richard W. Scott, Dorothy G. Flood

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 187 KB

english, 2000

47

FAD mutant PS-1 gene-targeted mice: increased Aβ42 and Aβ deposition without APP overproduction

Dorothy G Flood, Andrew G Reaume, Karen S Dorfman, Yin-Guo Lin, Diane M Lang, Stephen P Trusko, Mary J Savage, Wim G Annaert, Bart De Strooper, Robert Siman, Richard W Scott

Journal:

Neurobiology of Aging

Year:

2002

Language:

english

File:

PDF, 482 KB

english, 2002

48

O3-05-02 FAD-linked presenilin-1 mutations affect the N-cadherin/CBP signaling pathway via a loss-of-function mechanism

Philippe Marambaud, Paul H. Wen, Anindita Dutt, Junichi Shioi, Geo Serban, Akihiko Takashima, Robert Siman, Nikolaos K. Robakis

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 313 KB

english, 2004

49

O4-02-06 Gamma-secretase subunit composition and distribution in the presenilin wild-type and mutant mouse brain

Robert Siman, Sheryl Salidas

Journal:

Neurobiology of Aging

Year:

2004

Language:

english

File:

PDF, 321 KB

english, 2004

50

O2-02-03: Evidence that amyloid deposition impairs adult hippocampal neurogenesis

Robert Siman, Chen Zhang, Elizabeth McNeil, Lindsay Dressler, Antony Dang

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 70 KB

english, 2008